Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30107980 | 0.83 | ROCK1 (0.45) | KDM4EALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL30107982 | 0.82 | GAA (0.45) | MAPTKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30108028 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1NPC1HPGDL3MBTL1 | |
| SCHEMBL30107951 | 0.79 | PTGS1 (0.46) | MAPTKDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL30108023 | 0.78 | PTGS1 (0.47) | MAPTKDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL30107994 | 0.77 | PTGS1 (0.50) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL30107959 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL30108012 | 0.75 | TSHR (0.58) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30108014 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL30108046 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1NPC1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |