Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108002 | 0.84 | ADORA2A (0.37) | ADORA2AADORA1 | |
| SCHEMBL30108066 | 0.79 | ADORA2A (0.44) | ADORA2AADORA1 | |
| SCHEMBL30107964 | 0.75 | ADORA2A (0.46) | ADORA2AADORA1 | |
| SCHEMBL30108022 | 0.74 | SLC6A2 (0.37) | CHEK2ADORA2AADORA1 | |
| SCHEMBL30107942 | 0.73 | ADORA2A (0.47) | ADORA2AADORA1 | |
| SCHEMBL30108006 | 0.73 | CCNA2 (0.36) | ADORA2AADORA1 | |
| SCHEMBL30108062 | 0.68 | MAPT (0.39) | ADORA2AADORA1 | |
| SCHEMBL5118901 | 0.68 | CHEK2 (0.56) | SLC2A1CHEK2HDAC1GPR119ALOX5AP | |
| SCHEMBL6406782 | 0.68 | SLC2A1 (0.58) | SLC2A1CHEK2HDAC1GPR119 | |
| SCHEMBL22918743 | 0.68 | CHEK2 (0.52) | SLC2A1CHEK2HDAC1GPR119ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |