Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108062 | 0.88 | MAPT (0.39) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30107964 | 0.86 | ADORA2A (0.46) | ADORA2AADORA1ADORA3ADORA2BMET | |
| SCHEMBL30108034 | 0.86 | ALDH1A1 (0.37) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30107942 | 0.86 | ADORA2A (0.47) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30108043 | 0.85 | ADORA2A (0.41) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30108002 | 0.83 | ADORA2A (0.37) | ADORA2AADORA1 | |
| SCHEMBL30108054 | 0.79 | SLC2A1 (0.45) | ADORA2AADORA1 | |
| SCHEMBL30107951 | 0.77 | PTGS1 (0.46) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30108063 | 0.73 | KDM4E (0.40) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30108045 | 0.73 | ROCK1 (0.60) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |