Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108002 | 0.89 | ADORA2A (0.37) | SLC6A2SLC6A4KCNH2PRKCZHTR3A | |
| SCHEMBL30108043 | 0.82 | ADORA2A (0.41) | ADORA2AADORA1MAPK10 | |
| SCHEMBL30108077 | 0.81 | SLC6A2 (0.40) | SLC6A2SLC6A4KCNH2PRKCZHTR3A | |
| SCHEMBL30107952 | 0.78 | ADORA2A (0.41) | ADORA2AADORA1MAPK10 | |
| SCHEMBL30108049 | 0.77 | TSHR (0.45) | ADORA2AADORA1 | |
| SCHEMBL30108054 | 0.74 | SLC2A1 (0.45) | ADORA2AADORA1CHEK2 | |
| SCHEMBL30108066 | 0.71 | ADORA2A (0.44) | ADORA2AADORA1 | |
| SCHEMBL30108063 | 0.71 | KDM4E (0.40) | ADORA2AADORA1MAPK10 | |
| SCHEMBL30108021 | 0.70 | KDM4E (0.36) | SLC6A2SLC6A4KCNH2HTR3ACCNA2 | |
| SCHEMBL30107960 | 0.70 | SLC6A2 (0.40) | SLC6A2SLC6A4KCNH2PRKCZHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |