Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 11/20 | 0.77 |
| ▸ | MKNK2 | Q9HBH9 | 11/20 | 0.77 |
| ▸ | F7 | P08709 | 1/20 | 0.65 |
| ▸ | F3 | P13726 | 1/20 | 0.65 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.65 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.65 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.65 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.65 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.65 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.65 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.65 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.59 |
| ▸ | KMO | O15229 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188346 | 1.00 | MKNK1 (0.77) | MKNK1MKNK2F7F3SARM1 | |
| SCHEMBL608617 | 0.86 | KMO (0.73) | MKNK1MKNK2F7F3SARM1 | |
| SCHEMBL2488476 | 0.86 | MKNK1 (0.77) | MKNK1MKNK2SIRT2SIRT1SIRT3 | |
| SCHEMBL6754398 | 0.85 | MKNK1 (0.67) | MKNK1MKNK2F7F3SARM1 | |
| Hydrochloric Acid SCHEMBL30037096 | 0.85 | KMO (0.71) | MKNK1MKNK2F7F3SARM1 | |
| SCHEMBL1690466 | 0.84 | KMO (0.75) | MKNK1MKNK2KMOALDH1A1CYP1A2 | |
| SCHEMBL14621505 | 0.83 | MKNK1 (0.59) | MKNK1MKNK2KMOALDH1A1CYP1A2 | |
| SCHEMBL10028681 | 0.83 | KMO (0.73) | MKNK1MKNK2KMOALDH1A1CYP1A2 | |
| SCHEMBL10137211 | 0.83 | KMO (0.58) | MKNK1MKNK2F7F3SARM1 | |
| SCHEMBL606654 | 0.82 | MKNK1 (1.00) | MKNK1MKNK2F7F3SARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-01-14 | — | — | US | claimed |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2023-01-05 | — | — | US | claimed |
| WO-2025217420-A1 | PYRIDINONE COMPOUNDS, METHODS AND USES THEREOF | ZENO MANAGEMENT, INC. (US) | 2025-10-16 | — | — | WO | disclosed |
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-01-14 | — | — | US | disclosed |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | MERTK, ERBB2, SRC | MKNK1 151/4885MKNK2 190/4885F7 4842/4885 |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | MKNK1 151/4885MKNK2 190/4885F7 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.