⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30248639 | 1.00 | — | — | |
| SCHEMBL25169780 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL10453279 | 0.96 | — | — | |
| SCHEMBL28617873 | 0.93 | — | — | |
| Tris(Hydroxymethyl)Phosphine SCHEMBL28454283 | 0.80 | LMNA (0.38) | — | |
| SCHEMBL4478382 | 0.77 | LMNA (0.42) | — | |
| SCHEMBL836624 | 0.75 | — | — | |
| SCHEMBL25241362 | 0.75 | — | — | |
| SCHEMBL25227005 | 0.75 | — | — | |
| SCHEMBL3750293 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2026-01-20 | — | — | US | claimed |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-09 | — | — | US | claimed |
| EP-4171569-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | Council of Scientific & Industrial Research (IN) | 2023-05-03 | — | — | EP | claimed |
| WO-2022003712-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-01-06 | — | — | WO | claimed |
| CN-109771658-B | Targeted multi-arm conjugates | 博瑞生物医药（苏州）股份有限公司 | 2021-12-10 | — | — | CN | claimed |
| CN-109776787-B | Multi-arm targeting conjugates | 博瑞生物医药（苏州）股份有限公司 | 2021-08-03 | — | — | CN | claimed |
| EP-2440518-B1 | METHOD FOR MAKING FLUOROALKYL NITRILES | BAYER CROPSCIENCE AG (DE) | 2014-08-20 | — | — | EP | claimed |
| WO-2013109142-A1 | COMBINED PDK AND MAPK/ERK PATHWAY INHIBITION IN NEOPLASIA | STICHTING HET NEDERLANDS KANKER INSTITUUT (NL) | 2013-07-25 | — | — | WO | claimed |
| US-20130131375-A1 | PROCESS FOR PREPARING DIFLUOROACETIC ACID, SALTS THEREOF OR ESTERS THEREOF | RHODIA OPERATIONS (FR) | 2013-05-23 | — | — | US | claimed |
| EP-2245001-B1 | Method for the production of 2-fluoroacyl-3-amino-acrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-20 | — | — | EP | claimed |
| US-8203015-B2 | Process for preparing fluoroalkyl nitriles | BAYER CROPSCIENCE AG (DE) | 2012-06-19 | — | — | US | claimed |
| US-20120116068-A1 | METHOD FOR BREAKING DOWN CELLULOSE IN SOLUTION | BASF SE (DE) | 2012-05-10 | — | — | US | claimed |
| US-20110207694-A1 | MAMMALIAN HYPOTHALAMIC NUTRIENT MODULATION OF GLUCOSE METABOLISM | ROSSETTI LUCIANO | 2011-08-25 | — | — | US | claimed |
| US-20100312002-A1 | Process For Preparing Fluoroalkyl Nitriles | BAYER CROPSCIENCE AG (DE) | 2010-12-09 | — | — | US | claimed |
| US-20100274049-A1 | Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-28 | — | — | US | claimed |
| US-20090187016-A1 | METHOD FOR PRODUCING CELLULOSE ACETALS | BASF SE (DE) | 2009-07-23 | — | — | US | claimed |
| WO-2006119355-A2 | MAMMALIAN HYPOTHALAMIC NUTRIENT MODULATION OF GLUCOSE METABOLISM | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2006-11-09 | — | — | WO | claimed |
| WO-2001023618-A2 | COMPOSITIONS AND METHODS FOR REDUCING OLIGONUCLEOTIDE HYBRIDIZATION AND PRIMING SPECIFICITY | QIAGEN GENOMICS, INC. (US) | 2001-04-05 | — | — | WO | claimed |
| EP-0546669-B1 | Preparation of fluorine-doped tungstic oxide and glass coating process | FORD MOTOR CO (GB) | 1996-04-17 | — | — | EP | claimed |
| US-5248796-A | Antitumor agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-09-28 | — | — | US | claimed |