Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 10/20 | 0.66 |
| ▸ | NLRP3 | Q96P20 | 11/20 | 0.66 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30214838 | 1.00 | IL1B (0.66) | IL1BNLRP3KAT2B | |
| SCHEMBL26092308 | 1.00 | IL1B (0.66) | IL1BNLRP3KAT2B | |
| SCHEMBL26092302 | 1.00 | IL1B (0.66) | IL1BNLRP3KAT2B | |
| SCHEMBL26121073 | 0.90 | NLRP3 (0.60) | IL1BNLRP3KAT2B | |
| SCHEMBL29275956 | 0.90 | NLRP3 (0.68) | IL1BNLRP3KAT2B | |
| SCHEMBL29276173 | 0.90 | NLRP3 (0.68) | IL1BNLRP3KAT2B | |
| SCHEMBL26113433 | 0.89 | NLRP3 (0.57) | IL1BNLRP3KAT2B | |
| SCHEMBL24840289 | 0.89 | NLRP3 (0.79) | IL1BNLRP3KAT2B | |
| SCHEMBL30040144 | 0.89 | NLRP3 (0.79) | IL1BNLRP3KAT2B | |
| SCHEMBL24840759 | 0.89 | NLRP3 (0.79) | IL1BNLRP3KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-116102535-A | Nitrogen-containing compound, preparation method and application thereof | 索智生物科技（浙江）有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |