Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | DUT | P33316 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27256288 | 0.73 | GSK3A (0.46) | USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31078258 | 0.72 | IDO1 (0.43) | HRH3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10366086 | 0.71 | IDO1 (0.43) | HRH3CYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL28858018 | 0.70 | TAAR1 (0.75) | SIGMAR1KCNH2HRH3ALDH1A1TAAR1 | |
| SCHEMBL16968221 | 0.69 | DAO (0.58) | SIGMAR1KCNH2HRH3DAOUSP2 | |
| SCHEMBL15563710 | 0.69 | DAO (0.58) | SIGMAR1KCNH2HRH3DAOUSP2 | |
| SCHEMBL20435861 | 0.69 | AKR1B1 (0.56) | TSHRALDH1A1 | |
| SCHEMBL21352405 | 0.69 | MEN1 (0.39) | ALDH1A1LMNANPBWR1 | |
| SCHEMBL27546858 | 0.68 | GSK3A (0.49) | SIGMAR1DAOALDH1A1 | |
| SCHEMBL27501759 | 0.68 | SIGMAR1 (0.54) | SIGMAR1KCNH2HRH3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023276813-A1 | PYRIDAZINONE COMPOUND, AGRICULTURAL AND HORTICULTURAL GERMICIDE, NEMATICIDE, AND MEDICAL AND ANIMAL ANTIFUNGAL AGENT | 日本曹達株式会社 | 2023-01-05 | — | — | WO | disclosed |