Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | SORD | Q00796 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930263 | 1.00 | MAP1LC3B (0.57) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31282263 | 0.88 | ALDH1A1 (0.56) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL23964527 | 0.81 | MAP1LC3B (0.56) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL23964460 | 0.80 | MAP1LC3B (0.54) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL23964326 | 0.78 | MAP1LC3B (0.44) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL23964474 | 0.77 | MAP1LC3B (0.51) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31466697 | 0.75 | MAPT (0.46) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL26172949 | 0.74 | ALDH1A1 (0.44) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL30109387 | 0.74 | ALDH1A1 (0.44) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL3787335 | 0.74 | MAP1LC3B (1.00) | MAP1LC3BALDH1A1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427396-A | Compounds for preventing or treating lipid metabolism-related diseases | 复旦大学 | 2022-12-02 | — | — | CN | disclosed |