Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.53 |
| ▸ | PRKCI | P41743 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | CFB | P00751 | 6/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18479114 | 1.00 | AXL (0.53) | AXLPRKCIDYRK1AAHRCFB | |
| SCHEMBL2628869 | 0.85 | AXL (0.53) | AXLPRKCIDYRK1AAHRCFB | |
| SCHEMBL8737415 | 0.80 | AXL (0.47) | AXLPRKCIDYRK1ACFBCCR8 | |
| SCHEMBL12491288 | 0.80 | PRKCI (0.42) | AXLPRKCIDYRK1AAHRCCR8 | |
| SCHEMBL30855430 | 0.78 | DYRK1A (0.41) | AXLPRKCIDYRK1AAHRCCR8 | |
| SCHEMBL29197433 | 0.78 | DYRK1A (0.41) | AXLPRKCIDYRK1AAHRCCR8 | |
| SCHEMBL23912514 | 0.77 | PRKCI (0.40) | AXLPRKCIDYRK1AAHRCCR8 | |
| SCHEMBL19792317 | 0.77 | DYRK1A (0.40) | AXLPRKCIDYRK1AAHRCCR8 | |
| SCHEMBL30465845 | 0.77 | DYRK1A (0.40) | AXLPRKCIDYRK1AAHRCCR8 | |
| SCHEMBL25898918 | 0.77 | AXL (0.44) | AXLPRKCIDYRK1ACFBCCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667259-B | Fused ring compounds for inhibiting H-PGDS | 佐藤制药株式会社 | 2025-06-17 | — | — | CN | disclosed |
| CN-118401522-A | Azaindole derivatives inhibiting H-PGDS | 佐藤制药株式会社 | 2024-07-26 | — | — | CN | disclosed |
| CN-115667259-A | Condensed ring compounds for inhibiting H-PGDS | 佐藤制药株式会社 | 2023-01-31 | — | — | CN | disclosed |