Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | MAP4K3 | Q8IVH8 | 5/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.52 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.52 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.52 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.52 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 2/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.49 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15431234 | 0.87 | IRAK4 (0.61) | PIM1MAP4K3IRAK4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL15416021 | 0.86 | IRAK4 (0.60) | PIM1MAP4K3IRAK4CHRNB2CHRNA4 | |
| SCHEMBL2300261 | 0.85 | CHRNB2 (0.66) | MAP4K3IRAK4CHRNB2CHRNA4CYP1A2 | |
| SCHEMBL14688907 | 0.79 | PIM1 (1.00) | PIM1 | |
| SCHEMBL26818517 | 0.79 | IRAK4 (0.61) | MAP4K3IRAK4CHRNB2CHRNA4IRAK1 | |
| SCHEMBL16758530 | 0.78 | MET (0.64) | MAP4K3METALK | |
| SCHEMBL30108193 | 0.77 | PIM1 (0.52) | PIM1MAP4K3IRAK4CHRNB2CHRNA4 | |
| SCHEMBL16758540 | 0.77 | MET (0.63) | MAP4K3MET | |
| SCHEMBL14320710 | 0.77 | PIM1 (0.54) | PIM1MAP4K3IRAK4CHRNB2CHRNA4 | |
| SCHEMBL10040495 | 0.77 | ALK (0.59) | PIM1MAP4K3IRAK4CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156770-B | Aminopyridine derivatives as inhibitors of TAM family kinases | 圣诺康生命科学公司 | 2022-10-04 | — | — | CN | disclosed |