Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 5/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188503 | 1.00 | AURKA (0.58) | AURKACDK2AURKBMAPT | |
| SCHEMBL20188270 | 0.90 | — | — | |
| SCHEMBL30114704 | 0.90 | — | — | |
| SCHEMBL20188200 | 0.89 | AURKA (0.53) | AURKA | |
| SCHEMBL30114845 | 0.89 | AURKA (0.53) | AURKA | |
| SCHEMBL20196486 | 0.89 | AURKA (0.47) | AURKAMAPT | |
| SCHEMBL20188249 | 0.89 | AURKA (0.59) | AURKACDK2AURKBMAPT | |
| SCHEMBL30114870 | 0.89 | AURKA (0.47) | AURKAMAPT | |
| SCHEMBL20188007 | 0.85 | AURKA (0.45) | AURKA | |
| SCHEMBL20188260 | 0.85 | AURKA (0.58) | AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | claimed |
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | disclosed |