SCHEMBL30115002

SCHEMBL30115002

Cc1ccc(C(=O)O)cc1-c1ccc(/C=C2\SC(=O)N(c3ccccc3)C2=O)o1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 9/20 0.70
▸ KMT2A Q03164 9/20 0.70
▸ MEN1 O00255 8/20 0.70
▸ NPC1 O15118 3/20 0.70
▸ RAB9A P51151 3/20 0.70
▸ ALDH1A1 P00352 6/20 0.69
▸ MAPT P10636 6/20 0.69
▸ TDP1 Q9NUW8 6/20 0.69
▸ CTDSP1 Q9GZU7 4/20 0.69
▸ KDM4E B2RXH2 4/20 0.69
▸ APEX1 P27695 3/20 0.69
▸ HPGD P15428 2/20 0.69
▸ DNMT1 P26358 2/20 0.69
▸ RECQL P46063 2/20 0.69
▸ PSMD14 O00487 1/20 0.69
▸ MMP2 P08253 1/20 0.69
▸ L3MBTL1 Q9Y468 5/20 0.66
▸ PKM P14618 3/20 0.66
▸ PTGES O14684 1/20 0.66
▸ SAE1 Q9UBE0 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL46557 0.84 MEN1 (0.70) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL29665060 0.84 LCK (0.73) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL6397407 0.82 TDP1 (1.00) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL6397410 0.82 TDP1 (1.00) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL28362223 0.81 EP300 (0.65) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL29361837 0.80 POLB (0.88) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL31358741 0.80 POLB (0.70) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL5145169 0.79 KMT2A (0.88) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL6395526 0.79 KMT2A (0.88) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL6393332 0.78 POLB (0.71) POLBKMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141274-B Milk allergen beta-lactoglobulin specific nano-antibody and application thereof 南开大学 2024-02-20 — — CN claimed
CN-115141274-A Milk allergen beta-lactoglobulin specific nano antibody and application thereof 南开大学 2022-10-04 — — CN claimed
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF ADARX PHARMACEUTICALS, INC. (US) 2025-10-09 — — US disclosed
EP-4522628-A2 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF Adarx Pharmaceuticals, Inc. (US) 2025-03-19 — — EP disclosed
CN-119552241-A HIV-1 nano antibody, preparation method and application thereof 上海市重大传染病和生物安全研究院 2025-03-04 — — CN disclosed
CN-115141274-B Milk allergen beta-lactoglobulin specific nano-antibody and application thereof 南开大学 2024-02-20 — — CN disclosed
CN-115141274-B Milk allergen beta-lactoglobulin specific nano-antibody and application thereof 南开大学 2024-02-20 — — CN disclosed
WO-2023220737-A2 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF ADARX PHARMACEUTICALS, INC. (US) 2023-11-16 — — WO disclosed
CN-115141274-A Milk allergen beta-lactoglobulin specific nano antibody and application thereof 南开大学 2022-10-04 — — CN disclosed
CN-115141274-A Milk allergen beta-lactoglobulin specific nano antibody and application thereof 南开大学 2022-10-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF POLRMT, TARDBP, NSUN2 POLB 20/4885KMT2A 1256/4885MEN1 1631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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