Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 11/20 | 1.00 |
| ▸ | POLB | P06746 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 10/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 7/20 | 1.00 |
| ▸ | APEX1 | P27695 | 7/20 | 1.00 |
| ▸ | RECQL | P46063 | 6/20 | 1.00 |
| ▸ | DNMT1 | P26358 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | PSMD14 | O00487 | 1/20 | 1.00 |
| ▸ | MMP2 | P08253 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6397410 | 1.00 | TDP1 (1.00) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL30115002 | 0.82 | POLB (0.70) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL28362136 | 0.79 | EP300 (0.66) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL5143034 | 0.79 | POLB (0.65) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL5143032 | 0.79 | POLB (0.65) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL6397790 | 0.77 | MAPT (0.62) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL6397787 | 0.77 | MAPT (0.62) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL31358757 | 0.76 | MEN1 (1.00) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL6395805 | 0.75 | POLB (0.84) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL6395803 | 0.75 | POLB (0.84) | TDP1POLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282840-A1 | Methods of modulating neurotrophin-mediated activity | PAINCEPTOR PHARMA CORPORATION (CA) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282840-A1 | Methods of modulating neurotrophin-mediated activity | NGF, BDNF, NTRK2 | TDP1 1996/4885POLB 2945/4885ALDH1A1 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.