Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226379 | 1.00 | MCHR1 (0.49) | MCHR1TRPV1SNCAKIF11TDO2 | |
| SCHEMBL23226382 | 0.90 | PTPN1 (0.54) | MCHR1TRPV1STING1PTPN1PTPN6 | |
| SCHEMBL30116591 | 0.90 | PTPN1 (0.54) | MCHR1TRPV1STING1PTPN1PTPN6 | |
| SCHEMBL30116634 | 0.90 | STING1 (0.53) | MCHR1TRPV1SNCAKIF11STING1 | |
| SCHEMBL23226670 | 0.90 | STING1 (0.53) | MCHR1TRPV1SNCAKIF11STING1 | |
| SCHEMBL23226749 | 0.89 | TRPV1 (0.50) | MCHR1TRPV1SNCAKIF11TDO2 | |
| SCHEMBL30116569 | 0.89 | TRPV1 (0.50) | MCHR1TRPV1SNCAKIF11TDO2 | |
| SCHEMBL23226397 | 0.88 | MCHR1 (0.47) | MCHR1TRPV1TDO2STING1PTPN1 | |
| SCHEMBL23226495 | 0.88 | KIF11 (0.56) | MCHR1TRPV1SNCAKIF11TDO2 | |
| SCHEMBL23212320 | 0.82 | TRPV1 (0.46) | MCHR1TRPV1SNCAKIF11TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |