Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226670 | 1.00 | STING1 (0.53) | STING1ESR1MAPTMEN1NPC1 | |
| SCHEMBL23226379 | 0.90 | MCHR1 (0.49) | STING1ESR1MCHR1SNCATRPV1 | |
| SCHEMBL30116619 | 0.90 | MCHR1 (0.49) | STING1ESR1MCHR1SNCATRPV1 | |
| SCHEMBL30116639 | 0.89 | STING1 (0.66) | STING1ESR1MAPTMEN1NPC1 | |
| SCHEMBL23226392 | 0.89 | STING1 (0.66) | STING1ESR1MAPTMEN1NPC1 | |
| SCHEMBL23226481 | 0.87 | STING1 (0.52) | STING1MAPTMEN1NPC1LMNA | |
| SCHEMBL23226590 | 0.87 | STING1 (0.56) | STING1MAPTMEN1NPC1LMNA | |
| Hydrochloric Acid SCHEMBL30116673 | 0.86 | STING1 (0.55) | STING1MAPTMEN1NPC1LMNA | |
| SCHEMBL23212313 | 0.85 | KIF11 (0.60) | STING1MAPTMEN1NPC1LMNA | |
| SCHEMBL30116577 | 0.85 | KIF11 (0.60) | STING1MAPTMEN1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |