Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226392 | 1.00 | STING1 (0.66) | STING1PTPN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23226670 | 0.89 | STING1 (0.53) | STING1KMT2ALMNAMAPTSNCA | |
| SCHEMBL30116634 | 0.89 | STING1 (0.53) | STING1KMT2ALMNAMAPTSNCA | |
| SCHEMBL23226481 | 0.89 | STING1 (0.52) | STING1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL23226382 | 0.88 | PTPN1 (0.54) | STING1PTPN1MCHR1NPC1HTR2C | |
| SCHEMBL30116591 | 0.88 | PTPN1 (0.54) | STING1PTPN1MCHR1NPC1HTR2C | |
| SCHEMBL23226571 | 0.86 | STING1 (0.71) | STING1PTPN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23212652 | 0.85 | STING1 (0.72) | STING1PTPN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23226381 | 0.85 | STING1 (0.51) | STING1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL30116671 | 0.85 | STING1 (0.51) | STING1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |