Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226571 | 0.89 | STING1 (0.71) | STING1PTPN1KMT2AMAPTKDM4E | |
| SCHEMBL30116577 | 0.88 | KIF11 (0.60) | STING1KMT2AMAPTLMNASNCA | |
| SCHEMBL23212313 | 0.88 | KIF11 (0.60) | STING1KMT2AMAPTLMNASNCA | |
| SCHEMBL23226600 | 0.88 | STING1 (0.91) | STING1PTPN1KMT2AMAPTKDM4E | |
| SCHEMBL23226489 | 0.88 | STING1 (0.56) | STING1KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL30116613 | 0.85 | STING1 (0.82) | STING1PTPN1KMT2AMAPTKDM4E | |
| SCHEMBL23226665 | 0.85 | STING1 (0.82) | STING1PTPN1KMT2AMAPTKDM4E | |
| SCHEMBL23226392 | 0.85 | STING1 (0.66) | STING1PTPN1KMT2AMAPTKDM4E | |
| SCHEMBL30116639 | 0.85 | STING1 (0.66) | STING1PTPN1KMT2AMAPTKDM4E | |
| SCHEMBL23226363 | 0.84 | STING1 (0.88) | STING1PTPN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |