Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226636 | 1.00 | STING1 (0.75) | STING1HDAC1HDAC2PTPN1KCNK3 | |
| SCHEMBL30116581 | 0.86 | HDAC1 (0.65) | STING1HDAC1HDAC2PTPN1KMT2A | |
| SCHEMBL23212318 | 0.86 | HDAC1 (0.65) | STING1HDAC1HDAC2PTPN1KMT2A | |
| SCHEMBL29923263 | 0.86 | STING1 (1.00) | STING1PTPN1KCNK3KCNK9KMT2A | |
| SCHEMBL23226366 | 0.86 | STING1 (1.00) | STING1PTPN1KCNK3KCNK9KMT2A | |
| SCHEMBL23226675 | 0.85 | HDAC1 (0.79) | STING1HDAC1HDAC2PTPN1KMT2A | |
| SCHEMBL30116663 | 0.85 | HDAC1 (0.79) | STING1HDAC1HDAC2PTPN1KMT2A | |
| SCHEMBL23229660 | 0.85 | STING1 (0.66) | STING1HDAC1HDAC2PTPN1KCNK3 | |
| SCHEMBL7817331 | 0.84 | HDAC1 (0.69) | HDAC1HDAC2PTPN1KCNK3KCNK9 | |
| SCHEMBL23212652 | 0.82 | STING1 (0.72) | STING1PTPN1KCNK3KCNK9KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |