SCHEMBL7817331

SCHEMBL7817331

O=C(Nc1ccc(O)c(NC(=O)c2ccccc2)c1)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.69
KCNMA1 Q12791 2/20 0.69
HDAC2 Q92769 1/20 0.69
KMT2A Q03164 4/20 0.64
PKM P14618 1/20 0.64
GAA P10253 1/20 0.63
KCNK3 O14649 1/20 0.62
KCNK9 Q9NPC2 1/20 0.62
MAPT P10636 1/20 0.58
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
MEN1 O00255 2/20 0.58
PTPN1 P18031 1/20 0.58
SIRT1 Q96EB6 2/20 0.56
KDM4E B2RXH2 1/20 0.56
POLB P06746 1/20 0.56
ACE2 Q9BYF1 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13721353 0.88 HPSE (0.57) HDAC1KCNMA1HDAC2KMT2APKM
SCHEMBL11793228 0.86 KMT2A (0.73) KMT2APKMKCNK3KCNK9MAPT
SCHEMBL23226636 0.84 STING1 (0.75) HDAC1KCNMA1HDAC2KMT2AKCNK3
SCHEMBL30116655 0.84 STING1 (0.75) HDAC1KCNMA1HDAC2KMT2AKCNK3
SCHEMBL2380752 0.84 HDAC1 (0.71) HDAC1KCNMA1HDAC2KMT2APKM
SCHEMBL30842037 0.84 HPGD (0.58) HDAC1KCNMA1HDAC2KMT2APKM
SCHEMBL23212318 0.84 HDAC1 (0.65) HDAC1HDAC2KMT2AMAPTMEN1
SCHEMBL30116581 0.84 HDAC1 (0.65) HDAC1HDAC2KMT2AMAPTMEN1
SCHEMBL5178629 0.83 HDAC1 (0.69) HDAC1KCNMA1HDAC2KMT2APKM
SCHEMBL2605544 0.83 KCNMA1 (0.66) HDAC1KCNMA1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-7615324-B2 Photosensitive composition, and cured relief pattern production method and semiconductor device using the same FUJIFILM CORPORATION (JP) 2009-11-10 US disclosed
US-7615324-B2 Photosensitive composition, and cured relief pattern production method and semiconductor device using the same FUJIFILM CORPORATION (JP) 2009-11-10 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
US-7455948-B2 Photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2008-11-25 US disclosed
US-7455948-B2 Photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2008-11-25 US disclosed
US-20080227024-A1 PHOTOSENSITIVE COMPOSITION, AND CURED RELIEF PATTERN PRODUCTION METHOD AND SEMICONDUCTOR DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080227024-A1 PHOTOSENSITIVE COMPOSITION, AND CURED RELIEF PATTERN PRODUCTION METHOD AND SEMICONDUCTOR DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed
EP-0757682-B1 BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION FUJISAWA PHARMACEUTICAL CO (JP) 2001-06-20 EP disclosed
US-5858995-A ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0757682-A1 BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-02-12 EP disclosed
WO-1995029907-A1 BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 HDAC1 1079/4885KCNMA1 2570/4885HDAC2 987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.