Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30116981 | 0.96 | CYP3A4 (0.40) | EPHX2CYP3A4CYP2C19BRD4CREBBP | |
| SCHEMBL30116965 | 0.83 | P2RX7 (0.49) | EPHX2PPIAP2RX7 | |
| SCHEMBL30116961 | 0.79 | P2RX7 (0.47) | EPHX2P2RX7 | |
| SCHEMBL26051739 | 0.78 | EPHX2 (0.39) | EPHX2CYP3A4CYP2C19BRD4CREBBP | |
| SCHEMBL26097835 | 0.76 | MAPK14 (0.52) | EPHX2 | |
| SCHEMBL26051091 | 0.76 | EPHX2 (0.41) | EPHX2CYP3A4CYP2C19BRD4CREBBP | |
| SCHEMBL30116984 | 0.75 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL26098462 | 0.75 | P2RX7 (0.40) | EPHX2P2RX7 | |
| SCHEMBL25370529 | 0.74 | CYP3A4 (0.40) | EPHX2CYP3A4CYP2C19BRD4CREBBP | |
| SCHEMBL30580204 | 0.74 | CYP3A4 (0.40) | EPHX2CYP3A4CYP2C19BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461327-A | Spiro urea derivatives | 爱杜西亚药品有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-115461327-A | Spiro urea derivatives | 爱杜西亚药品有限公司 | 2022-12-09 | — | — | CN | disclosed |