Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370529 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2C19NTRK1RIPK1BRD4 | |
| SCHEMBL26051091 | 0.81 | EPHX2 (0.41) | CYP3A4CYP2C19NTRK1RIPK1BRD4 | |
| SCHEMBL30580183 | 0.80 | P2RX7 (0.35) | EPHX2 | |
| SCHEMBL25370780 | 0.80 | P2RX7 (0.35) | EPHX2 | |
| SCHEMBL30229676 | 0.76 | MAPK14 (0.53) | EPHX2ROCK2ROCK1NAMPT | |
| SCHEMBL25370459 | 0.76 | MAPK14 (0.53) | EPHX2ROCK2ROCK1NAMPT | |
| SCHEMBL30117005 | 0.74 | EPHX2 (0.40) | CYP3A4CYP2C19NTRK1RIPK1BRD4 | |
| SCHEMBL26051736 | 0.73 | NTRK1 (0.38) | CYP3A4CYP2C19NTRK1RIPK1BRD4 | |
| SCHEMBL30116981 | 0.73 | CYP3A4 (0.40) | CYP3A4CYP2C19NTRK1BRD4CREBBP | |
| SCHEMBL26051739 | 0.73 | EPHX2 (0.39) | CYP3A4CYP2C19NTRK1RIPK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479377-A1 | NEW BICYCLOPENTANE DERIVATIVES | Icagen, LLC (US) | 2024-12-25 | — | — | EP | disclosed |
| CN-118829626-A | Novel dicyclopentane derivatives | 伊卡根有限责任公司 | 2024-10-22 | — | — | CN | disclosed |
| WO-2023158584-A1 | NEW BICYCLOPENTANE DERIVATIVES | ICAGEN, LLC (US) | 2023-08-24 | — | — | WO | disclosed |