Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659870 | 0.79 | TP53 (0.46) | HTR2CHTR2BHTR2AALDH1A1LMNA | |
| SCHEMBL29427088 | 0.77 | KDM1A (0.50) | MAP1LC3BKDM1ABRD4HTR2CHTR2B | |
| SCHEMBL10046437 | 0.77 | KDM1A (0.50) | MAP1LC3BKDM1ABRD4HTR2CHTR2B | |
| SCHEMBL8036501 | 0.74 | AKR1C3 (0.52) | LMNARAB9ANPC1 | |
| Formic Acid SCHEMBL27536018 | 0.71 | MAP1LC3B (0.43) | MAP1LC3BKDM1ABRD4HTR2CHTR2B | |
| SCHEMBL3048438 | 0.71 | KDM1A (0.43) | MAP1LC3BKDM1ABRD4HTR2CHTR2B | |
| Formic Acid SCHEMBL28217657 | 0.70 | MAP1LC3B (0.42) | MAP1LC3BKDM1ABRD4HTR2CHTR2B | |
| SCHEMBL28336863 | 0.70 | MAP1LC3B (0.39) | MAP1LC3BKDM1ABRD4HTR2CHTR2B | |
| SCHEMBL28217656 | 0.69 | MAP1LC3B (0.41) | MAP1LC3BKDM1ABRD4HTR2CHTR2B | |
| SCHEMBL25604023 | 0.69 | KDM1A (0.47) | MAP1LC3BKDM1ABRD4HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065230-A1 | THERAPEUTIC COMPOUNDS | Genentech, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |