Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 7/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23926361 | 1.00 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TP53RORCKDM4E | |
| SCHEMBL23926360 | 0.88 | TP53 (0.35) | ALDH1A1TP53RORCKDM4EHPGD | |
| SCHEMBL30118899 | 0.88 | TP53 (0.35) | ALDH1A1TP53RORCKDM4EHPGD | |
| SCHEMBL30118953 | 0.87 | KDM4E (0.41) | ALDH1A1SMN1; SMN2TP53RORCKDM4E | |
| SCHEMBL23926351 | 0.87 | KDM4E (0.41) | ALDH1A1SMN1; SMN2TP53RORCKDM4E | |
| SCHEMBL23926329 | 0.84 | HPGD (0.41) | ALDH1A1SMN1; SMN2TP53RORCKDM4E | |
| SCHEMBL30118905 | 0.84 | HPGD (0.41) | ALDH1A1SMN1; SMN2TP53RORCKDM4E | |
| SCHEMBL23926379 | 0.83 | KDM4E (0.39) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL30118895 | 0.83 | KDM4E (0.39) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL23926372 | 0.81 | RORC (0.37) | ALDH1A1SMN1; SMN2TP53RORCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667256-A | Compounds for treating diseases and methods of treating diseases | 艾特里提治疗有限公司 | 2023-01-31 | — | — | CN | disclosed |