Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22406342 | 1.00 | KMT2A (0.51) | KMT2ACES2CES1HSD17B14L3MBTL1 | |
| SCHEMBL8710005 | 0.82 | KMT2A (0.58) | KMT2ACES2CES1HSD17B14L3MBTL1 | |
| SCHEMBL30118935 | 0.82 | KMT2A (0.58) | KMT2ACES2CES1HSD17B14L3MBTL1 | |
| SCHEMBL22426344 | 0.81 | P2RX1 (0.40) | KMT2AL3MBTL1ALDH1A1RAB9AKDM4E | |
| SCHEMBL28255112 | 0.80 | KDM4C (0.47) | KMT2AL3MBTL1ALDH1A1RAB9AKDM4E | |
| SCHEMBL22406359 | 0.79 | P2RX7 (0.44) | KMT2ACES1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL22406337 | 0.78 | RAB9A (0.60) | KMT2ACES2CES1ALDH1A1RAB9A | |
| SCHEMBL30118904 | 0.78 | RAB9A (0.60) | KMT2ACES2CES1ALDH1A1RAB9A | |
| SCHEMBL31369148 | 0.75 | KMT2A (0.75) | KMT2ACES2CES1HSD17B14L3MBTL1 | |
| SCHEMBL87791 | 0.75 | KMT2A (0.75) | KMT2ACES2CES1HSD17B14L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667256-A | Compounds for treating diseases and methods of treating diseases | 艾特里提治疗有限公司 | 2023-01-31 | — | — | CN | disclosed |