SCHEMBL30119829

SCHEMBL30119829

CN(C)CCNCc1ccc(CN)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.49
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TERT O14746 1/20 0.45
SIGMAR1 Q99720 1/20 0.44
KDM6B O15054 1/20 0.43
KDM4A O75164 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43
OPRM1 P35372 1/20 0.42
OPRK1 P41145 1/20 0.42
HDAC1 Q13547 1/20 0.40
TPSAB1 Q15661 2/20 0.40
CHRM2 P08172 1/20 0.40
ANPEP P15144 1/20 0.40
ERAP2 Q6P179 1/20 0.40
MAP4K4 O95819 1/20 0.40
BRAF P15056 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
HRH4 Q9H3N8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10054980 0.90 SIGMAR1 (0.50) CYP2C9CYP2C19TERTSIGMAR1OPRM1
SCHEMBL27208122 0.89 TDP1 (0.50) KEAP1NFE2L2TERTSIGMAR1KDM6B
SCHEMBL18434706 0.89 CYP2C9 (0.63) CYP2C9CYP2C19TERTSIGMAR1OPRM1
SCHEMBL30119905 0.86 TERT (0.48) KEAP1NFE2L2CYP2C9CYP2C19TERT
SCHEMBL13102974 0.82 CHRM2 (0.60) TERTSIGMAR1OPRM1OPRK1HDAC1
SCHEMBL10535689 0.81 CHRM2 (0.58) SIGMAR1CHRM2TDP1
SCHEMBL18434292 0.81 CARM1 (0.48) CYP2C9CYP2C19TERTSIGMAR1OPRM1
SCHEMBL3879539 0.81 CHEK1 (0.48) TERTSIGMAR1OPRM1OPRK1HDAC1
SCHEMBL3037243 0.81 TAAR1 (0.57) CYP2C19TERTSIGMAR1OPRM1OPRK1
SCHEMBL16268751 0.81 CHRM2 (0.58) CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370578-A1 ACCELERATOR FOR EPOXY RESINS Sika Technology AG (CH) 2024-05-22 EP claimed
WO-2023285188-A1 ACCELERATOR FOR EPOXY RESINS SIKA TECHNOLOGY AG (CH) 2023-01-19 WO claimed
EP-4119592-A1 ACCELERATOR FOR EPOXIDE RESINS Sika Technology AG (CH) 2023-01-18 EP claimed
EP-4370578-A1 ACCELERATOR FOR EPOXY RESINS Sika Technology AG (CH) 2024-05-22 EP disclosed
WO-2023285188-A1 ACCELERATOR FOR EPOXY RESINS SIKA TECHNOLOGY AG (CH) 2023-01-19 WO disclosed