Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 7/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281295 | 0.90 | PDK4 (0.42) | STSESR2PDK4GPR119NR1H2 | |
| SCHEMBL3434214 | 0.87 | STS (0.39) | STSESR2PDK4CA12CA1 | |
| SCHEMBL23442704 | 0.83 | PDK4 (0.39) | STSPDK4GPR119MAPTHTR6 | |
| SCHEMBL19979152 | 0.81 | GPR119 (0.42) | STSESR2PDK4CA12CA1 | |
| SCHEMBL30273556 | 0.79 | MEN1 (0.43) | PDK4CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL30595934 | 0.77 | NR1H2 (0.32) | STSNR1H2 | |
| SCHEMBL3664972 | 0.76 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL1439920 | 0.76 | ESR2 (0.39) | STSESR2USP2SMN1; SMN2GPR119 | |
| SCHEMBL212403 | 0.76 | PDK4 (0.46) | STSESR2PDK4GPR119NR1H2 | |
| SCHEMBL30120197 | 0.76 | GPR119 (0.37) | STSUSP2SMN1; SMN2GPR119RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351583-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |