Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.37 |
| ▸ | RORC | P51449 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24753745 | 0.83 | GPR119 (0.43) | GPR119USP2SMN1; SMN2STS | |
| SCHEMBL30120123 | 0.76 | STS (0.36) | GPR119RORCUSP2SMN1; SMN2STS | |
| SCHEMBL4281295 | 0.75 | PDK4 (0.42) | GPR119STS | |
| SCHEMBL31510813 | 0.73 | RORC (0.37) | GPR119RORCSTSTACR1 | |
| SCHEMBL23442704 | 0.73 | PDK4 (0.39) | GPR119STS | |
| SCHEMBL27168224 | 0.72 | RORC (0.30) | RORC | |
| SCHEMBL16064117 | 0.71 | RORC (0.41) | GPR119RORCSTSTACR1 | |
| SCHEMBL26136551 | 0.70 | GPR119 (0.39) | GPR119RORCUSP2SMN1; SMN2STS | |
| SCHEMBL23541220 | 0.69 | RORC (0.34) | RORCSTS | |
| SCHEMBL30595934 | 0.69 | NR1H2 (0.32) | STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351583-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |