Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23799119 | 1.00 | CRBN (0.53) | CRBNDDB1HDAC8 | |
| SCHEMBL31334549 | 0.94 | CRBN (0.48) | CRBNDDB1HDAC8 | |
| SCHEMBL30915148 | 0.91 | CRBN (0.51) | CRBNDDB1HDAC8 | |
| SCHEMBL31390678 | 0.88 | CRBN (0.49) | CRBNDDB1HDAC8 | |
| SCHEMBL31334208 | 0.88 | CRBN (0.49) | CRBNDDB1HDAC8 | |
| SCHEMBL23540366 | 0.88 | CRBN (0.49) | CRBNDDB1HDAC8 | |
| SCHEMBL23551320 | 0.88 | CRBN (0.49) | CRBNDDB1HDAC8 | |
| SCHEMBL23551319 | 0.88 | CRBN (0.49) | CRBNDDB1HDAC8 | |
| SCHEMBL30120249 | 0.88 | CRBN (0.49) | CRBNDDB1HDAC8 | |
| SCHEMBL30120231 | 0.88 | CRBN (0.49) | CRBNDDB1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351583-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |