Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30120484 | 0.94 | CRBN (0.53) | CRBNDDB1HDAC8 | |
| SCHEMBL23799119 | 0.94 | CRBN (0.53) | CRBNDDB1HDAC8 | |
| SCHEMBL31334803 | 0.91 | CRBN (0.47) | CRBNDDB1HDAC8LMNA | |
| SCHEMBL31334208 | 0.91 | CRBN (0.49) | CRBNDDB1HDAC8 | |
| SCHEMBL31639383 | 0.91 | CRBN (0.46) | CRBNDDB1HDAC8CDK9LMNA | |
| SCHEMBL27162923 | 0.90 | DDB1 (0.59) | CRBNDDB1LMNA | |
| SCHEMBL31701449 | 0.90 | DDB1 (0.59) | CRBNDDB1LMNA | |
| SCHEMBL31334160 | 0.89 | DDB1 (0.57) | CRBNDDB1 | |
| SCHEMBL31333583 | 0.89 | CRBN (0.46) | CRBNDDB1LMNA | |
| SCHEMBL30135825 | 0.88 | CRBN (0.47) | CRBNDDB1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |