Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26521621 | 1.00 | ALDH1A1 (0.47) | ALDH1A1ALPLKMT2AALPIMEN1 | |
| SCHEMBL26098118 | 0.93 | ALDH1A1 (0.45) | ALDH1A1ALPLKMT2AALPIMEN1 | |
| SCHEMBL26521619 | 0.92 | ALDH1A1 (0.47) | ALDH1A1ALPLKMT2AALPIMEN1 | |
| SCHEMBL30132092 | 0.92 | ALDH1A1 (0.47) | ALDH1A1ALPLKMT2AALPIMEN1 | |
| SCHEMBL30120633 | 0.87 | ALDH1A1 (0.45) | ALDH1A1ALPLKMT2AALPIMEN1 | |
| SCHEMBL26521633 | 0.87 | ALDH1A1 (0.45) | ALDH1A1ALPLKMT2AALPIMEN1 | |
| SCHEMBL23749872 | 0.87 | ALDH1A1 (0.45) | ALDH1A1ALPLKMT2AALPILMNA | |
| SCHEMBL30120702 | 0.87 | ALDH1A1 (0.45) | ALDH1A1ALPLKMT2AALPILMNA | |
| SCHEMBL23723550 | 0.83 | ALPL (0.48) | ALDH1A1ALPLKMT2AALPILMNA | |
| SCHEMBL30120689 | 0.83 | ALPL (0.48) | ALDH1A1ALPLKMT2AALPILMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397423-A | Combination therapy for the treatment of MPS1 | 增益治疗股份有限公司 | 2022-11-25 | — | — | CN | disclosed |