Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16236082 | 1.00 | ABL1 (0.48) | ABL1MTORRAB9ADAPK3MAP4K4 | |
| SCHEMBL16236916 | 0.93 | MTOR (0.50) | ABL1MTORRAB9ADAPK3MAP4K4 | |
| SCHEMBL24650664 | 0.87 | MTOR (0.54) | ABL1MTORRAB9ADAPK3MAP4K4 | |
| SCHEMBL24651203 | 0.86 | ABL1 (0.49) | ABL1MTORRAB9ADAPK3MAP4K4 | |
| SCHEMBL16236759 | 0.85 | ADK (0.47) | ABL1DAPK3MAP4K4PAK4LCK | |
| SCHEMBL19743546 | 0.85 | MTOR (0.52) | ABL1MTORRAB9ADAPK3MAP4K4 | |
| SCHEMBL1940882 | 0.84 | ABL1 (0.64) | ABL1MTORRAB9ADAPK3MAP4K4 | |
| SCHEMBL30155310 | 0.84 | ABL1 (0.64) | ABL1MTORRAB9ADAPK3MAP4K4 | |
| SCHEMBL29484468 | 0.84 | SRC (0.61) | ABL1MTORRAB9ADAPK3MAP4K4 | |
| SCHEMBL400626 | 0.84 | SRC (0.61) | ABL1MTORRAB9ADAPK3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |