Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCRL2 | O00421 | 1/20 | 0.37 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24651193 | 1.00 | CCRL2 (0.37) | CCRL2EIF2AK3CSF1RCYP1A2CYP3A4 | |
| SCHEMBL24651054 | 0.82 | EIF2AK3 (0.43) | EIF2AK3CSF1RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30120820 | 0.82 | EIF2AK3 (0.43) | EIF2AK3CSF1RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30367510 | 0.73 | BTK (0.41) | KMT2A | |
| SCHEMBL29998362 | 0.70 | EGFR (0.41) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL24096504 | 0.70 | EGFR (0.41) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL24651143 | 0.70 | CYP1A2 (0.46) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL24650695 | 0.70 | EIF2AK3 (0.47) | EIF2AK3CYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL30120848 | 0.70 | EIF2AK3 (0.47) | EIF2AK3CYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL24651144 | 0.69 | NPC1 (0.43) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |