Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.74 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.64 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | UGCG | Q16739 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691413 | 1.00 | MAPK14 (0.74) | MAPK14SCN5ASCN9ARIPK2RAB9A | |
| SCHEMBL18172045 | 0.89 | MAPK14 (0.79) | MAPK14SCN5ASCN9ARIPK2LMNA | |
| SCHEMBL1691845 | 0.85 | MAPK14 (0.56) | MAPK14SCN5ASCN9ARIPK2RAB9A | |
| SCHEMBL17844090 | 0.83 | ALDH1A1 (0.67) | MAPK14SCN5ASCN9ARAB9ALMNA | |
| SCHEMBL1457162 | 0.82 | MAPK14 (0.62) | MAPK14SCN5ASCN9ALMNAALDH1A1 | |
| SCHEMBL169884 | 0.82 | MAPK14 (0.55) | MAPK14SCN5ASCN9ALMNASMN1; SMN2 | |
| SCHEMBL8034944 | 0.82 | SCN9A (0.56) | MAPK14SCN5ASCN9ARIPK2RAB9A | |
| SCHEMBL971001 | 0.81 | MAPK14 (0.72) | MAPK14SCN5ASCN9ARIPK2RAB9A | |
| SCHEMBL1691804 | 0.81 | RIPK2 (0.67) | MAPK14SCN5ASCN9ARIPK2RAB9A | |
| SCHEMBL1691798 | 0.80 | RIPK2 (0.61) | MAPK14SCN5ASCN9ARIPK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |
| CN-115397423-A | Combination therapy for the treatment of MPS1 | 增益治疗股份有限公司 | 2022-11-25 | — | — | CN | disclosed |