SCHEMBL3012161

SCHEMBL3012161

CCOC(=O)C1C(C(=O)OCC)N2C=CN1CC2

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
ALDH1A1 P00352 9/20 0.41
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3007851 0.81 KDM4E (0.37) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL3016601 0.77 MAPT (0.46) MAPTALDH1A1GAAHSD17B10SMN1; SMN2
SCHEMBL3013693 0.76 MAPT (0.42) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL3009541 0.75 ALDH1A1 (0.39) MAPTALDH1A1KMT2AKDM4ESMN1; SMN2
SCHEMBL3017836 0.72 MAPT (0.42) MAPTALDH1A1KDM4EGAASMN1; SMN2
SCHEMBL1615657 0.71 MAPT (0.45) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL24708386 0.69 MAPT (0.40) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL8049474 0.68 MAPT (0.42) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL12123892 0.68 MAPT (0.42) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL12123897 0.68 MAPT (0.42) MAPTALDH1A1KDM4EGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100204438-A1 METHOD FOR PRODUCING TEDA DERIVATIVES BASF SE (DE) 2010-08-12 US disclosed
EP-2197882-A2 METHOD FOR PRODUCING TEDA DERIVATIVES Basf Se (DE) 2010-06-23 EP disclosed
WO-2009030649-A2 METHOD FOR PRODUCING TEDA DERIVATIVES BASF SE (DE) 2009-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204438-A1 METHOD FOR PRODUCING TEDA DERIVATIVES TES, TRRAP, NAAA MAPT 1647/4885ALDH1A1 720/4885MEN1 1202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.