SCHEMBL30121628

SCHEMBL30121628

CC(C)[Si](/C=C1\OC(=O)C=C1C1CCCC1)(C(C)C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
PTPN1 P18031 2/20 0.33
PTPRC P08575 1/20 0.33
PTPRF P10586 1/20 0.33
CDC25B P30305 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30121517 0.98 PTPN1 (0.35) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL30121742 0.76 CEL (0.31)
SCHEMBL30121888 0.74 CEL (0.34)
SCHEMBL30121620 0.74
SCHEMBL27893146 0.69 MAOA (0.45) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL30121669 0.69
SCHEMBL1898536 0.68 PTPN1 (0.44) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL10962139 0.65 MAOA (0.41) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL27509578 0.65 MAOA (0.41) MAOAMAOBPTPN1PTPRCPTPRF
Maleic Anhydride SCHEMBL27689320 0.62 MAOA (0.43) MAOAMAOBPTPN1PTPRCPTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370490-A1 LIGAND-CONTROLLED DIVERGENT DEHYDROGENATIVE REACTIONS OF ALIPHATIC ACIDS The Scripps Research Institute (US) 2024-05-22 EP disclosed
WO-2023287964-A1 LIGAND-CONTROLLED DIVERGENT DEHYDROGENATIVE REACTIONS OF ALIPHATIC ACIDS THE SCRIPPS RESEARCH INSTITUTE (US) 2023-01-19 WO disclosed