Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695961 | 1.00 | POLB (0.42) | POLBGAALRRK2PIK3CDPIK3CA | |
| SCHEMBL24696107 | 1.00 | POLB (0.42) | POLBGAALRRK2PIK3CDPIK3CA | |
| SCHEMBL16716432 | 0.93 | POLB (0.47) | POLBALOX5APFEN1ALDH1A1 | |
| SCHEMBL24695573 | 0.86 | POLB (0.41) | POLBGAA | |
| SCHEMBL30122146 | 0.86 | POLB (0.41) | POLBGAA | |
| SCHEMBL24696197 | 0.86 | POLB (0.41) | POLBGAA | |
| SCHEMBL30122147 | 0.86 | POLB (0.41) | POLBGAA | |
| SCHEMBL21586201 | 0.85 | POLB (0.38) | POLB | |
| SCHEMBL24696189 | 0.85 | POLB (0.38) | POLB | |
| SCHEMBL30122145 | 0.85 | POLB (0.38) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347591-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2024-04-10 | — | — | EP | claimed |
| WO-2022253841-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-08 | — | — | WO | claimed |
| WO-2025061707-A1 | SYNTHESIS OF SULFOXIMINES CONTAINING A BENZIMIDAZOLE MOIETY | SYNGENTA CROP PROTECTION AG (CH) | 2025-03-27 | — | — | WO | disclosed |
| US-20250081967-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2025-03-13 | — | — | US | disclosed |
| EP-4347591-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022253841-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250081967-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | DDT, AADAC, SMOX | POLB 4001/4885GAA 1306/4885LRRK2 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.