Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695961 | 0.93 | POLB (0.42) | POLBALOX5APFEN1ALDH1A1 | |
| SCHEMBL30122227 | 0.93 | POLB (0.42) | POLBALOX5APFEN1ALDH1A1 | |
| SCHEMBL24696107 | 0.93 | POLB (0.42) | POLBALOX5APFEN1ALDH1A1 | |
| SCHEMBL25184184 | 0.90 | POLB (0.41) | POLBCRHR1 | |
| SCHEMBL29360277 | 0.89 | POLB (0.48) | POLBALOX5APFEN1MEN1KMT2A | |
| SCHEMBL14684583 | 0.89 | POLB (0.48) | POLBALOX5APFEN1MEN1KMT2A | |
| SCHEMBL24696197 | 0.87 | POLB (0.41) | POLB | |
| SCHEMBL30122147 | 0.87 | POLB (0.41) | POLB | |
| SCHEMBL24695573 | 0.87 | POLB (0.41) | POLB | |
| SCHEMBL30122146 | 0.87 | POLB (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068780-B1 | PESTICIDALLY ACTIVE BICYCLIC HETEROCYCLES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-14 | — | — | EP | disclosed |
| US-9522913-B2 | Pesticidally active bicyclic heterocycles with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-20 | — | — | US | disclosed |
| US-9522913-B2 | Pesticidally active bicyclic heterocycles with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-20 | — | — | US | disclosed |
| US-20160272638-A1 | PESTICIDALLY ACTIVE BICYCLIC HETEROCYCLES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-22 | — | — | US | disclosed |
| US-20160272638-A1 | PESTICIDALLY ACTIVE BICYCLIC HETEROCYCLES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-22 | — | — | US | disclosed |
| WO-2015071180-A1 | PESTICIDALLY ACTIVE BICYCLIC HETEROCYCLES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-21 | — | — | WO | disclosed |
| EP-2873668-A1 | Pesticidally active bicyclic heterocycles with sulphur containing substituents | Syngenta Participations AG. (CH) | 2015-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272638-A1 | PESTICIDALLY ACTIVE BICYCLIC HETEROCYCLES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, TST | POLB 4206/4885ALOX5AP 2804/4885FEN1 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.