Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326799 | 0.89 | ADORA1 (0.47) | MAT2AADORA1PKMRXFP1BRD9 | |
| SCHEMBL30122338 | 0.75 | RXFP1 (0.35) | MAT2APKMRXFP1ALDH1A1GAA | |
| SCHEMBL25112474 | 0.69 | ADORA1 (0.35) | ADORA1LMNA | |
| SCHEMBL24671864 | 0.67 | ADORA1 (0.43) | MAT2AADORA1BRD9BRD7ALDH1A1 | |
| SCHEMBL23326564 | 0.67 | DYRK1A (0.38) | MAT2AADORA1DYRK1A | |
| SCHEMBL29918643 | 0.67 | ADORA1 (0.43) | MAT2AADORA1BRD9BRD7ALDH1A1 | |
| SCHEMBL23326645 | 0.67 | RXFP1 (0.40) | MAT2APKMRXFP1BRD9BRD7 | |
| SCHEMBL29861864 | 0.67 | RXFP1 (0.40) | MAT2APKMRXFP1BRD9BRD7 | |
| SCHEMBL28863519 | 0.66 | ADORA1 (0.39) | ADORA1BRD9ALDH1A1GAAHPGD | |
| SCHEMBL29861478 | 0.66 | ADORA1 (0.41) | ADORA1BRD9DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212531-A1 | PYRIDOPYRIMIDINONE COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2022-10-06 | — | — | WO | disclosed |