Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCND2 | P30279 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326799 | 0.78 | ADORA1 (0.47) | ADORA1CDK4CCND1CCND2CCND3 | |
| SCHEMBL25112473 | 0.73 | CNR2 (0.36) | CNR2LMNA | |
| SCHEMBL30122255 | 0.69 | MAT2A (0.42) | ADORA1LMNA | |
| SCHEMBL29861478 | 0.68 | ADORA1 (0.41) | ADORA1ADORA2ACDK4CCND1CCND2 | |
| SCHEMBL28863519 | 0.68 | ADORA1 (0.39) | ADORA1MAPTENPP1CDK4CCND1 | |
| SCHEMBL10042029 | 0.66 | FADS1 (0.49) | MAPTPTGS2TSHR | |
| SCHEMBL25462029 | 0.63 | CDK4 (0.55) | ADORA1CDK4CCND1CCND2CCND3 | |
| SCHEMBL29861616 | 0.63 | CDK4 (0.55) | ADORA1CDK4CCND1CCND2CCND3 | |
| SCHEMBL24671864 | 0.63 | ADORA1 (0.43) | ADORA1MAPTENPP1CDK4CCND1 | |
| SCHEMBL29918643 | 0.63 | ADORA1 (0.43) | ADORA1MAPTENPP1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4148056-A1 | SOS1 INHIBITOR CONTAINING PHOSPHORUS | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-03-15 | — | — | EP | disclosed |