Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326645 | 0.90 | RXFP1 (0.40) | RXFP1PKMPIK3CAALDH1A1GAA | |
| SCHEMBL29861864 | 0.90 | RXFP1 (0.40) | RXFP1PKMPIK3CAALDH1A1GAA | |
| SCHEMBL30122319 | 0.80 | CA1 (0.31) | — | |
| SCHEMBL30122280 | 0.80 | PIK3CA (0.34) | RXFP1PIK3CAALDH1A1GAAHPGD | |
| SCHEMBL25743161 | 0.76 | PIK3CA (0.41) | RXFP1PKMPIK3CAALDH1A1GAA | |
| SCHEMBL30122255 | 0.75 | MAT2A (0.42) | RXFP1PKMALDH1A1GAAHPGD | |
| SCHEMBL24582789 | 0.70 | PKM (0.35) | RXFP1PKMMAT2A | |
| SCHEMBL29918620 | 0.70 | CRHR1 (0.31) | PIK3CA | |
| SCHEMBL25396743 | 0.70 | ALDH1A1 (0.38) | RXFP1PIK3CAALDH1A1GAAHPGD | |
| SCHEMBL23326846 | 0.69 | POLB (0.38) | RXFP1PKMALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212531-A1 | PYRIDOPYRIMIDINONE COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2022-10-06 | — | — | WO | disclosed |