Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESRRA | P11474 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29861520 | 0.89 | PIK3CA (0.36) | PIK3CAKDM4EALDH1A1GLAGAA | |
| SCHEMBL23326861 | 0.89 | PIK3CA (0.36) | PIK3CAKDM4EALDH1A1GLAGAA | |
| SCHEMBL30122338 | 0.80 | RXFP1 (0.35) | PIK3CAKDM4EALDH1A1GLAGAA | |
| SCHEMBL30122319 | 0.72 | CA1 (0.31) | — | |
| SCHEMBL23326638 | 0.71 | KDM4E (0.35) | PIK3CAKDM4EALDH1A1GLAGAA | |
| SCHEMBL29910267 | 0.71 | KDM4E (0.35) | PIK3CAKDM4EALDH1A1GLAGAA | |
| SCHEMBL23326645 | 0.69 | RXFP1 (0.40) | PIK3CAKDM4EALDH1A1GLAGAA | |
| SCHEMBL24582788 | 0.69 | CDK4 (0.32) | — | |
| SCHEMBL29861864 | 0.69 | RXFP1 (0.40) | PIK3CAKDM4EALDH1A1GLAGAA | |
| SCHEMBL23326640 | 0.68 | CYP1A2 (0.33) | PIK3CAALDH1A1HSD17B10ESR1ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212531-A1 | PYRIDOPYRIMIDINONE COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2022-10-06 | — | — | WO | disclosed |