SCHEMBL30123343

SCHEMBL30123343

N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)NCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 13/20 0.47
▸ OPRM1 P35372 9/20 0.47
▸ OPRK1 P41145 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30007693 0.95 OPRD1 (0.48) OPRD1OPRM1OPRK1
SCHEMBL29587542 0.94 OPRD1 (0.52) OPRD1OPRM1OPRK1
SCHEMBL30010932 0.91 OPRD1 (0.48) OPRD1OPRM1OPRK1
SCHEMBL31256968 0.90 OPRD1 (0.46) OPRD1OPRM1
SCHEMBL30059073 0.88 — —
SCHEMBL30666352 0.86 OPRD1 (0.33) OPRD1OPRM1
SCHEMBL31553196 0.86 YARS1 (0.46) OPRD1OPRM1
SCHEMBL30627705 0.86 PTGS1 (0.35) OPRD1OPRM1OPRK1
SCHEMBL29630845 0.86 PTGS1 (0.35) OPRD1OPRM1OPRK1
SCHEMBL31031516 0.86 OPRD1 (0.51) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 — — EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 — — WO disclosed
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