⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31256968 | 0.90 | OPRD1 (0.46) | — | |
| SCHEMBL30592734 | 0.89 | NPY4R (0.47) | — | |
| SCHEMBL29884151 | 0.89 | NPY4R (0.47) | — | |
| SCHEMBL31553196 | 0.89 | YARS1 (0.46) | — | |
| SCHEMBL29540760 | 0.88 | GHSR (0.49) | — | |
| SCHEMBL29882201 | 0.88 | ENPEP (0.46) | — | |
| SCHEMBL31259944 | 0.88 | MME (0.47) | — | |
| SCHEMBL38650869 | 0.88 | MME (0.47) | — | |
| SCHEMBL31006409 | 0.88 | MME (0.47) | — | |
| SCHEMBL30123343 | 0.88 | OPRD1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279051-A1 | METHODS FOR THE TREATMENT OF MITOCHONDRIAL DISEASE | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230190859-A1 | METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-06-22 | — | — | US | disclosed |
| EP-4085920-A1 | METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Stealth BioTherapeutics Inc. (US) | 2022-11-09 | — | — | EP | disclosed |