SCHEMBL30123433

SCHEMBL30123433

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 2/20 0.42
▸ CAPN1 P07384 4/20 0.42
▸ CTSB P07858 2/20 0.42
▸ DPP3 Q9NY33 1/20 0.41
▸ LNPEP Q9UIQ6 3/20 0.41
▸ ANPEP P15144 1/20 0.40
▸ OPRM1 P35372 1/20 0.39
▸ OPRD1 P41143 1/20 0.39
▸ APLNR P35414 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29590728 0.88 CAPN1 (0.48) SLC6A2CAPN1CTSBDPP3LNPEP
SCHEMBL29630574 0.86 CAPN1 (0.49) SLC6A2CAPN1CTSBDPP3
SCHEMBL30785948 0.85 SLC6A2 (0.58) SLC6A2DPP3LNPEPANPEPOPRM1
SCHEMBL29566393 0.84 OPRM1 (0.44) OPRM1OPRD1
SCHEMBL29649761 0.84 OPRM1 (0.44) OPRM1OPRD1
SCHEMBL30254274 0.84 OPRM1 (0.50) SLC6A2OPRM1OPRD1
SCHEMBL31538915 0.83 SLC6A2 (0.51) SLC6A2DPP3LNPEPANPEPOPRM1
SCHEMBL30253903 0.83 SLC6A2 (0.51) SLC6A2OPRM1OPRD1
SCHEMBL18696882 0.83 AGTR1 (0.42) LNPEPANPEP
SCHEMBL31090172 0.82 SLC6A2 (0.64) SLC6A2DPP3LNPEPANPEPOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 — — EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 — — WO disclosed
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