SCHEMBL30123487

SCHEMBL30123487

NC(=O)CC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 2/20 0.59
▸ OPRD1 P41143 2/20 0.59
▸ ERAP1 Q9NZ08 2/20 0.59
▸ ERAP2 Q6P179 2/20 0.59
▸ LNPEP Q9UIQ6 1/20 0.59
▸ NPY1R P25929 1/20 0.59
▸ NPY2R P49146 1/20 0.59
▸ NPY4R P50391 1/20 0.59
▸ IL1RN P18510 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362220 0.97 OPRM1 (0.59) OPRM1OPRD1ERAP1ERAP2LNPEP
SCHEMBL30567443 0.94 NPY1R (0.62) ERAP1ERAP2LNPEPNPY1RNPY2R
SCHEMBL30799782 0.93 NPY1R (0.63) NPY1RNPY2RNPY4R
SCHEMBL22366988 0.92 GHSR (0.57) OPRM1OPRD1
SCHEMBL22366987 0.92 GHSR (0.57) OPRM1OPRD1
SCHEMBL29577129 0.92 ERAP1 (0.68) OPRM1OPRD1ERAP1ERAP2LNPEP
SCHEMBL29577668 0.92 ERAP1 (0.68) OPRM1OPRD1ERAP1ERAP2LNPEP
SCHEMBL30010303 0.92 ERAP1 (0.68) OPRM1OPRD1ERAP1ERAP2LNPEP
SCHEMBL31483387 0.91 ERAP2 (0.62) OPRM1OPRD1ERAP1ERAP2LNPEP
SCHEMBL29578349 0.91 OPRM1 (0.67) OPRM1OPRD1ERAP1ERAP2LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 — — EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 — — WO disclosed
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