SCHEMBL30123554

SCHEMBL30123554

O=C1OCc2cc(Oc3ccccc3)ccc21

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 12/20 0.64
MAOB P27338 12/20 0.64
MAPT P10636 2/20 0.53
LMNA P02545 2/20 0.53
GAA P10253 1/20 0.53
PRF1 P14222 2/20 0.48
PDE4A P27815 1/20 0.48
PDE4B Q07343 1/20 0.48
PDE4C Q08493 1/20 0.48
PDE4D Q08499 1/20 0.48
RECQL P46063 1/20 0.47
GSTP1 P09211 1/20 0.47
ALDH1A1 P00352 1/20 0.46
SLC9A3 P48764 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15268421 1.00 MAOA (0.64) MAOAMAOBMAPTLMNAGAA
SCHEMBL23929409 0.91 MAOA (0.56) MAOAMAOBMAPTLMNAGAA
SCHEMBL30123469 0.87 MAOA (0.70) MAOAMAOB
SCHEMBL20425169 0.87 MAOA (0.70) MAOAMAOB
Diphenylether SCHEMBL9513504 0.84 MAOA (0.74) MAOAMAOBMAPTLMNAGAA
SCHEMBL21662902 0.84 MAOA (0.54) MAOAMAOBMAPTLMNAGAA
SCHEMBL28914301 0.83 PRF1 (0.59) MAOAMAOBMAPTLMNAGAA
SCHEMBL29933676 0.83 PRF1 (0.59) MAOAMAOBMAPTLMNAGAA
SCHEMBL26124650 0.82 PRF1 (0.60) MAOAMAOBMAPTLMNAGAA
SCHEMBL14605693 0.81 MAOA (0.57) MAOAMAOBMAPTGAAPRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118165365-A Preparation method and application of composite heat stabilizer 万华化学集团股份有限公司 2024-06-11 CN claimed
CN-110225753-B Process for preparing 5-phenoxy-1 (3H) isobenzofuranones 金凯(辽宁)生命科技股份有限公司 2022-12-09 CN claimed
CN-115838354-B Thyroid hormone receptor beta agonist compound and preparation method and application thereof 中国科学院广州生物医药与健康研究院 2025-05-13 CN disclosed
EP-3573615-B1 A PROCESS FOR PREPARING 5-PHENOXY-1(3H)ISOBENZOFURANONE KINGCHEM LIFE SCIENCE LLC (US) 2024-06-12 EP disclosed
EP-3573615-C0 A PROCESS FOR PREPARING 5-PHENOXY-1(3H)ISOBENZOFURANONE KINGCHEM LIFE SCIENCE LLC (US) 2024-06-12 EP disclosed
CN-118165365-A Preparation method and application of composite heat stabilizer 万华化学集团股份有限公司 2024-06-11 CN disclosed
CN-115867537-A Improved process for the preparation of a rasagiline base 迈兰实验室有限公司 2023-03-28 CN disclosed
CN-115838354-A Thyroid hormone receptor beta agonist compound and preparation method and application thereof 中国科学院广州生物医药与健康研究院 2023-03-24 CN disclosed
CN-110225753-B Process for preparing 5-phenoxy-1 (3H) isobenzofuranones 金凯(辽宁)生命科技股份有限公司 2022-12-09 CN disclosed
CN-110225753-B Process for preparing 5-phenoxy-1 (3H) isobenzofuranones 金凯(辽宁)生命科技股份有限公司 2022-12-09 CN disclosed