Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 14/20 | 0.56 |
| ▸ | MAOB | P27338 | 14/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PRF1 | P14222 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15268421 | 0.91 | MAOA (0.64) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL30123554 | 0.91 | MAOA (0.64) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL87174 | 0.83 | MAPT (0.61) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL29492902 | 0.83 | MAPT (0.61) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL30123469 | 0.79 | MAOA (0.70) | MAOAMAOB | |
| SCHEMBL20425169 | 0.79 | MAOA (0.70) | MAOAMAOB | |
| Diphenylether SCHEMBL9513504 | 0.77 | MAOA (0.74) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL21662902 | 0.77 | MAOA (0.54) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL29933676 | 0.76 | PRF1 (0.59) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL28914301 | 0.76 | PRF1 (0.59) | MAOAMAOBMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214785-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ROXADUSTAT | MYLAN LABORATORIES LIMITED (IN) | 2021-10-28 | — | — | WO | disclosed |