Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.37 |
| ▸ | HTR3B | O95264 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24719517 | 1.00 | SLC6A2 (0.42) | SLC6A2SLC6A3HSP90AA1HSP90AB1HTR3E | |
| Bromide SCHEMBL29182849 | 0.99 | SLC6A2 (0.41) | SLC6A2SLC6A3HSP90AA1HSP90AB1HTR3E | |
| SCHEMBL30931122 | 0.80 | HTR7 (0.44) | SLC6A2SLC6A3HTR3ASCDHTR6 | |
| SCHEMBL30931000 | 0.76 | HTR7 (0.51) | SLC6A2SLC6A3HSP90AA1HSP90AB1HTR3E | |
| SCHEMBL30124547 | 0.76 | SMARCA2 (0.46) | ALDH1A1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL29182705 | 0.76 | SMARCA2 (0.46) | ALDH1A1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL24719664 | 0.75 | MAPKAPK2 (0.45) | — | |
| SCHEMBL30124692 | 0.75 | MAPKAPK2 (0.45) | — | |
| SCHEMBL24720721 | 0.75 | RPS6KA3 (0.37) | SLC6A2SLC6A3ALDH1A1HTR7 | |
| SCHEMBL24719652 | 0.74 | MAPKAPK2 (0.38) | SLC6A2SLC6A3HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351560-A1 | ANTICANCER COMPOUNDS | The Regents of the University of California (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-117794525-A | Anticancer compounds | 加利福尼亚大学董事会 | 2024-03-29 | — | — | CN | disclosed |
| WO-2022261204-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |