Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.83 |
| ▸ | KDR | P35968 | 4/20 | 0.83 |
| ▸ | FBP1 | P09467 | 2/20 | 0.83 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.83 |
| ▸ | AURKA | O14965 | 1/20 | 0.83 |
| ▸ | INSR | P06213 | 1/20 | 0.83 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.83 |
| ▸ | FLT4 | P35916 | 1/20 | 0.83 |
| ▸ | CLK1 | P49759 | 1/20 | 0.83 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.83 |
| ▸ | TEK | Q02763 | 1/20 | 0.83 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.83 |
| ▸ | RAF1 | P04049 | 1/20 | 0.76 |
| ▸ | BRAF | P15056 | 1/20 | 0.76 |
| ▸ | RET | P07949 | 2/20 | 0.72 |
| ▸ | KIF5B | P33176 | 2/20 | 0.72 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.72 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.72 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.68 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679736 | 1.00 | EGFR (0.83) | EGFRKDRFBP1ERBB2AURKA | |
| SCHEMBL8383 | 1.00 | EGFR (0.83) | EGFRKDRFBP1ERBB2AURKA | |
| Hydrochloric Acid SCHEMBL28040041 | 0.99 | EGFR (0.81) | EGFRKDRFBP1ERBB2AURKA | |
| Hydrochloric Acid SCHEMBL27915151 | 0.98 | EGFR (0.80) | EGFRKDRFBP1ERBB2AURKA | |
| SCHEMBL3238800 | 0.96 | EGFR (0.83) | EGFRKDRFBP1ERBB2AURKA | |
| Acetic Acid SCHEMBL29234690 | 0.95 | EGFR (0.75) | EGFRKDRFBP1ERBB2AURKA | |
| SCHEMBL13006609 | 0.93 | EGFR (0.71) | EGFRKDRFBP1ERBB2AURKA | |
| SCHEMBL14515606 | 0.91 | KDR (0.72) | EGFRKDRFBP1ERBB2AURKA | |
| SCHEMBL2099106 | 0.91 | EGFR (1.00) | EGFRKDRFBP1ERBB2AURKA | |
| SCHEMBL30505605 | 0.91 | EGFR (1.00) | EGFRKDRFBP1ERBB2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283977-A1 | USE OF PREPARATION FOR INHIBITING OR BLOCKING INTERACTION BETWEEN FAAH AND NLRP3 | 华南理工大学 | 2023-01-19 | — | — | WO | disclosed |
| CN-115616216-A | Use of an agent that inhibits or blocks the interaction between FAAH and NLRP3 | 华南理工大学 | 2023-01-17 | — | — | CN | disclosed |